9DPE
CryoEM Structure of Human BTN2A1 ectodomain in complex with TCR-blocking 2A1.12 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Butyrophilin subfamily 2 member A1 | polymer | 231 | 25741.4 | 1 | UniProt (Q7KYR7) Pfam (PF07686) Pfam (PF22705) | Homo sapiens (human) | |
| 2 | B (H) | Human IgG1 Fragment Antibody Heavy Chain | polymer | 233 | 24775.5 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | Human IgG1 Fragment Antibody Light Chain | polymer | 215 | 23258.8 | 1 | Homo sapiens (human) | ||
| 4 | D (N) | Human variable heavy-chain domain Nanobody | polymer | 136 | 15071.4 | 1 | Homo sapiens (human) | ||
| 5 | E, F, G, H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A: 1 - 219 (UniProt: Q7KYR7)
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gly 220 | - | expression tag |
| Ser 221 | - | expression tag |
| Gly 222 | - | expression tag |
| Leu 223 | - | expression tag |
| Glu 224 | - | expression tag |
| Val 225 | - | expression tag |
| Leu 226 | - | expression tag |
| Phe 227 | - | expression tag |
| Gln 228 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88847.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 89731.9 |
