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9DPD

Cryo-EM structure of SerRS dimer in complex with one SIRT2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, D)
Serine--tRNA ligase, cytoplasmicpolymer51458863.22UniProt (P49591)Homo sapiens (human)Seryl-tRNA synthetase,SerRS,Seryl-tRNA(Ser/Sec) synthetase
2C
(C)
NAD-dependent protein deacetylase sirtuin-2polymer38943233.11UniProt (Q8IXJ6)Homo sapiens (human)NAD-dependent protein defatty-acylase sirtuin-2,Regulatory protein SIR2 homolog 2,SIR2-like protein 2
3D
(C)
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATEnon-polymer559.31Chemie (AR6)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight160959.5
Non-Polymers*Number of molecules1
Total formula weight559.3
All*Total formula weight161518.8
*Water molecules are not included.

250835

PDB entries from 2026-03-18

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