9DON
Crystal structure of eIF4e in complex with Compound 5-PA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Eukaryotic translation initiation factor 4E | polymer | 191 | 22290.3 | 2 | UniProt (P06730) Pfam (PF01652) | Homo sapiens (human) | eIF4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein |
| 2 | C (A) | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE | non-polymer | 458.2 | 1 | Chemie (M7G) | |||
| 3 | D (B) | 2-[3-[[2-azanyl-7-[(5-chloranyl-1-benzofuran-2-yl)methyl]-6-oxidanylidene-1~{H}-purin-9-yl]methyl]phenyl]ethylphosphonic acid | non-polymer | 514.9 | 1 | Chemie (A1A8P) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 217 (UniProt: P06730)
| PDB | External Database | Details |
|---|---|---|
| Met 27 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44580.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 973.1 | |
| All* | Total formula weight | 45553.8 |
