9DOC

The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, at 1.2 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcription factor ETV6,Capillary morphogenesis gene 2 protein	polymer	268	30234.4	1	UniProt (P41212) UniProt (P58335) Pfam (PF02198) Pfam (PF00092)	Homo sapiens (human)
2	B (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	C, D (A)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	E, F, G, H, I... (A)	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG)
5	L, M, N, O, P (A)	SODIUM ION	non-polymer		23.0	5	Chemie (NA)
6	Q (A)	water	water		18.0	245	Chemie (HOH)

Sequence modifications

A: 13 - 87 (UniProt: P41212)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 46	Arg 80	engineered mutation
Glu 78	Val 112	engineered mutation
Ala 88	-	linker
Gln 89	-	linker
Ala 90	-	linker
Arg 91	-	linker
Thr 92	-	linker
Val 93	-	linker

A: 94 - 268 (UniProt: P58335)

PDB	External Database	Details
Ala 226	Cys 175	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	30234.4
Non-Polymers*	Number of molecules	15
	Total formula weight	567.1
All*	Total formula weight	30801.5

*Water molecules are not included.