9DNM
Structure of rat beta-arrestin 1 bound to allosteric inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | anti-BRIL Fab Heavy chain | polymer | 225 | 23904.7 | 1 | Homo sapiens | ||
| 2 | B (L) | anti-BRIL Fab Light chain | polymer | 212 | 23209.8 | 1 | Homo sapiens | ||
| 3 | C (A) | Beta-arrestin-1,Soluble cytochrome b562 | polymer | 494 | 55727.2 | 1 | UniProt (P29066) UniProt (P0ABE7) Pfam (PF00339) Pfam (PF02752) | Rattus norvegicus (Norway rat) | Arrestin beta-1,Cytochrome b-562 |
| 4 | D (A) | (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one | non-polymer | 366.4 | 1 | Chemie (ODN) |
Sequence modifications
A: 2 - 176 (UniProt: P29066)
A: 177 - 282 (UniProt: P0ABE7)
A: 283 - 494 (UniProt: P29066)
| PDB | External Database | Details |
|---|---|---|
| Leu 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Trp 183 | Met 29 | engineered mutation |
| Ile 278 | His 124 | engineered mutation |
| Leu 282 | Arg 128 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asp 434 | Gly 333 | engineered mutation |
| Tyr 435 | Leu 334 | engineered mutation |
| Lys 436 | Leu 335 | engineered mutation |
| Asp 437 | Gly 336 | engineered mutation |
| Asp 439 | Leu 338 | engineered mutation |
| Asp 440 | Ala 339 | engineered mutation |
| Lys 441 | Ser 340 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 102841.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 366.4 | |
| All* | Total formula weight | 103208.1 |
