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9DMU

Cryo-EM structure of IMPDH2 bound to IMP and GAD

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Inosine-5'-monophosphate dehydrogenase 2polymer51856233.28UniProt (P12268)
Pfam (PF00478)
Pfam (PF00571)
Homo sapiens (human)IMPDH 2,IMPDH-II
2AA, EA, I, L, O...
(G, H, A, B, C...)
INOSINIC ACIDnon-polymer348.28Chemie (IMP)
3BA, FA, J, M, P...
(G, H, A, B, C...)
[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-[3-(thiophen-2-ylcarbonylamino)pyridin-1-yl]oxolan-2-yl]methyl hydrogen phosphatenon-polymer746.68Chemie (A1A7T)
4CA, DA, K, N, Q...
(G, H, A, B, C...)
POTASSIUM IONnon-polymer39.18Chemie (K)
5GA, HA, IA, JA, KA...
(A, B, C, D, E...)
waterwater18.0756Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 514 (UniProt: P12268)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
Gly -1-expression tag
Arg 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight449865.9
Non-Polymers*Number of molecules24
Total formula weight9070.9
All*Total formula weight458936.8
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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