9DMS
Human muscle nAChR with fab6-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Acetylcholine receptor subunit alpha | polymer | 457 | 51889.3 | 2 | UniProt (P02708) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 2 | C (E) | Acetylcholine receptor subunit beta | polymer | 503 | 57000.4 | 1 | UniProt (P11230) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 3 | D (D) | Acetylcholine receptor subunit delta | polymer | 517 | 58955.8 | 1 | UniProt (Q07001) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 4 | E (B) | Acetylcholine receptor subunit epsilon | polymer | 493 | 54743.8 | 1 | UniProt (Q04844) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 5 | F (F) | Fab6 heavy chain | polymer | 290 | 31441.9 | 1 | Homo sapiens (human) | ||
| 6 | G (G) | Fab6 light chain | polymer | 233 | 24977.6 | 1 | Homo sapiens (human) | ||
| 7 | H, I, J, K (H, I, J, K) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 4 | In PDB GlyTouCan (G22768VO) | |||
| 8 | L (L) | alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G51945PF) | |||
| 9 | M, Q, R, T, U (C, D, B) | CHOLESTEROL | non-polymer | 386.7 | 5 | Chemie (CLR) | |||
| 10 | N, P, V, W (D, B) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 4 | Chemie (POV) | |||
| 11 | O, S (D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 12 | AA, BA, CA, X, Y... (D, F, G, A, C...) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
E: -22 - 478 (UniProt: P11230)
| PDB | External Database | Details |
|---|---|---|
| Ser 479 | - | expression tag |
| Arg 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 330898.0 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 4554.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 5416.0 | |
| All* | Total formula weight | 340868.1 |
