9DMQ
Human muscle nAChR with fab3-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Acetylcholine receptor subunit alpha | polymer | 457 | 51889.3 | 2 | UniProt (P02708) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 2 | C (E) | Acetylcholine receptor subunit beta | polymer | 503 | 57000.4 | 1 | UniProt (P11230) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 3 | D (D) | Acetylcholine receptor subunit delta | polymer | 517 | 58955.8 | 1 | UniProt (Q07001) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 4 | E (B) | Acetylcholine receptor subunit epsilon | polymer | 493 | 54743.8 | 1 | UniProt (Q04844) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 5 | F (F) | Fab3 heavy chain | polymer | 275 | 29644.3 | 1 | Homo sapiens (human) | ||
| 6 | G (G) | Fab3 light chain | polymer | 235 | 25758.7 | 1 | Homo sapiens (human) | ||
| 7 | H, N (H, N) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 8 | I (I) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
| 9 | J, L (J, L) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 2 | In PDB GlyTouCan (G09724ZC) | |||
| 10 | K, M (K, M) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 11 | O (A) | ACETYLCHOLINE | non-polymer | 146.2 | 1 | Chemie (ACH) | |||
| 12 | P, S, U, V, X... (E, D, B) | CHOLESTEROL | non-polymer | 386.7 | 6 | Chemie (CLR) | |||
| 13 | Q, T, W, Z (E, D, B) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 4 | Chemie (POV) | |||
| 14 | R (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 15 | AA (B) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
E: -22 - 478 (UniProt: P11230)
| PDB | External Database | Details |
|---|---|---|
| Ser 479 | - | expression tag |
| Arg 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 329881.5 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 6051.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5727.6 | |
| All* | Total formula weight | 341660.7 |
