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9DMI

Structure of the C-terminal half of LRRK2 bound to RN277 (Type-II inhibitor)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leucine-rich repeat serine/threonine-protein kinase 2polymer1195136174.81UniProt (Q5S007)Homo sapiens (human)Dardarin
2B
(B)
E11 DARPinpolymer18219766.91synthetic construct
3C
(A)
N-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-{(3M)-3-[2-chloro-4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl}ureanon-polymer585.11Chemie (A1A7Q)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight155941.7
Non-Polymers*Number of molecules1
Total formula weight585.1
All*Total formula weight156526.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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