9DMB
Rhesus RHA10.01 Fab in complex with HIV-1 Env BG505 DS-SOSIP trimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, B, D) | RHA10.01 Light chain | polymer | 219 | 23852.6 | 3 | Macaca mulatta | ||
| 2 | B, E, H (C, G, H) | RHA10.01 Heavy chain | polymer | 243 | 26059.3 | 3 | Macaca mulatta | ||
| 3 | C, F, I (E, I, J) | BG505 DS-SOSIP glycoprotein gp41 | polymer | 153 | 17146.5 | 3 | UniProt (Q2N0S5) UniProt (by SIFTS) (A0ABF7PQ88) | Human immunodeficiency virus 1 | |
| 4 | J, K, L (L, F, K) | Envelope glycoprotein gp120 | polymer | 480 | 53929.1 | 3 | UniProt (Q2N0S6) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 5 | AA, GA, JA, KA, M... (a, g, j, k, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 6 | CA, EA, LA, N, OA... (c, e, l, N, o...) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 9 | In PDB GlyTouCan (G22768VO) | |||
| 7 | BA, DA, FA, HA, IA... (b, d, f, h, i...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 15 | In PDB GlyTouCan (G15407YE) | |||
| 8 | AB, BB, CB, DB, EB... (J, L, F, K, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 27 | Chemie (NAG) |
Sequence modifications
E, I, J: 512 - 664 (UniProt: Q2N0S5)
L, F, K: 31 - 512 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | engineered mutation |
| Cys 605 | Thr 602 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Cys 201 | Ile 200 | conflict |
| Asn 332 | Thr 330 | conflict |
| Cys 433 | Ala 430 | conflict |
| Cys 501 | Ala 498 | conflict |
| Arg 509 | Glu 506 | conflict |
| Arg 510 | Lys 507 | conflict |
| Arg 512 | Ala 509 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 362962.7 | |
| Branched | Number of molecules | 36 |
| Total formula weight | 22088.3 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 5972.6 | |
| All* | Total formula weight | 391023.7 |
