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9DLV

Cryo-EM structure of the human TREX-2.1 complex (LENG8/PCID2/DSS1) bound to DDX39B(UAP56)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leukocyte receptor cluster member 8polymer31635909.31UniProt (Q96PV6)
Pfam (PF03399)
Homo sapiens (human)
2B
(B)
PCI domain-containing protein 2polymer39946095.91UniProt (Q5JVF3)
Pfam (PF01399)
Homo sapiens (human)CSN12-like protein
3C
(C)
26S proteasome complex subunit SEM1polymer708284.61UniProt (P60896)
Pfam (PF05160)
Homo sapiens (human)26S proteasome complex subunit DSS1,Deleted in split hand/split foot protein 1,Split hand/foot deleted protein 1,Split hand/foot malformation type 1 protein
4D
(D)
Spliceosome RNA helicase DDX39Bpolymer43349567.91UniProt (Q13838)
Pfam (PF00270)
Pfam (PF00271)
Homo sapiens (human)56 kDa U2AF65-associated protein,ATP-dependent RNA helicase p47,DEAD box protein UAP56,HLA-B-associated transcript 1 protein
Sequence modifications
A: 490 - 800 (UniProt: Q96PV6)
PDBExternal DatabaseDetails
Gly 485-expression tag
Ala 486-expression tag
Met 487-expression tag
Gly 488-expression tag
Ser 489-expression tag
D: 1 - 428 (UniProt: Q13838)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
A1amm 108Glu 108conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight139857.7
All*Total formula weight139857.7
*Water molecules are not included.

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PDB entries from 2026-02-18

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