9DLR
Cryo-EM structure of the human TREX-2.1 complex (LENG8/PCID2/DSS1) bound to the N-terminal motif of DDX39B(UAP56)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leukocyte receptor cluster member 8 | polymer | 316 | 35909.3 | 1 | UniProt (Q96PV6) Pfam (PF03399) | Homo sapiens (human) | |
| 2 | B (B) | PCI domain-containing protein 2 | polymer | 399 | 46095.9 | 1 | UniProt (Q5JVF3) Pfam (PF01399) | Homo sapiens (human) | CSN12-like protein |
| 3 | C (C) | 26S proteasome complex subunit SEM1 | polymer | 70 | 8284.6 | 1 | UniProt (P60896) Pfam (PF05160) | Homo sapiens (human) | 26S proteasome complex subunit DSS1,Deleted in split hand/split foot protein 1,Split hand/foot deleted protein 1,Split hand/foot malformation type 1 protein |
| 4 | D (D) | Spliceosome RNA helicase DDX39B | polymer | 428 | 49056.3 | 1 | UniProt (Q13838) Pfam (PF00270) Pfam (PF00271) | Homo sapiens (human) | 56 kDa U2AF65-associated protein,ATP-dependent RNA helicase p47,DEAD box protein UAP56,HLA-B-associated transcript 1 protein |
Sequence modifications
A: 490 - 800 (UniProt: Q96PV6)
| PDB | External Database | Details |
|---|---|---|
| Gly 485 | - | expression tag |
| Ala 486 | - | expression tag |
| Met 487 | - | expression tag |
| Gly 488 | - | expression tag |
| Ser 489 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 139346.0 | |
| All* | Total formula weight | 139346.0 |
