9DL1
Crystal Structure of HLA-A*02:01/NY-ESO-1 (SLLMWITQV) and a target specific TRACeR-I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | TRACeR-I | polymer | 132 | 16145.4 | 2 | Homo sapiens | ||
| 2 | B, F (B, F) | MHC class I antigen, A-2 alpha chain | polymer | 276 | 31985.4 | 2 | UniProt (A0A5B8RNS7) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 4 | E, H (E, H) | Cancer/testis antigen 1 | polymer | 9 | 1090.3 | 2 | UniProt (P78358) | Homo sapiens | Autoimmunogenic cancer/testis antigen NY-ESO-1,Cancer/testis antigen 6.1,CT6.1,L antigen family member 2,LAGE-2 |
| 5 | I, J, K (B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 522 | Chemie (HOH) |
Sequence modifications
B, F: 1 - 275 (UniProt: A0A5B8RNS7)
C, G: 1 - 99 (UniProt: P61769)
E, H: 1 - 8 (UniProt: P78358)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Val 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 122201.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 122489.2 |
