9DL0
Crystal structure of a synthetic Fab (R3H8) in complex with the FRB domain of mTOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, H) | Fab heavy chain | polymer | 224 | 23536.2 | 2 | Homo sapiens | ||
| 2 | B, D (G, I) | Serine/threonine-protein kinase mTOR | polymer | 98 | 11606.2 | 2 | UniProt (P42345) Pfam (PF08771) | Homo sapiens (human) | FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,Mammalian target of rapamycin,mTOR,Mechanistic target of rapamycin,Rapamycin and FKBP12 target 1,Rapamycin target protein 1 |
| 3 | E, F (Y, Z) | Fab light chain | polymer | 212 | 23082.6 | 2 | Homo sapiens | ||
| 4 | G, H, I, J, K... (A, G, H, I, Y...) | water | water | 18.0 | 373 | Chemie (HOH) |
Sequence modifications
G, I: 2021 - 2113 (UniProt: P42345)
| PDB | External Database | Details |
|---|---|---|
| Ser 2020 | - | expression tag |
| Gly 2114 | - | expression tag |
| Gly 2115 | - | expression tag |
| Gly 2116 | - | expression tag |
| Gly 2117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 116450.1 | |
| All* | Total formula weight | 116450.1 |
