9DKW

Human mitochondrial ClpP in complex with Bortezomib

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	ATP-dependent Clp protease proteolytic subunit, mitochondrial	polymer	221	24179.9	14	UniProt (Q16740) Pfam (PF00574)	Homo sapiens (human)	Endopeptidase Clp
2	AA, BA, O, P, Q... (M, N, A, B, C...)	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	non-polymer		384.2	14	Chemie (BO2)
3	CA, DA, EA, FA, GA... (A, B, C, D, E...)	water	water		18.0	168	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N: 58 - 277 (UniProt: Q16740)

PDB	External Database	Details
Ser 57	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	338518.3
Non-Polymers*	Number of molecules	14
	Total formula weight	5379.3
All*	Total formula weight	343897.6

*Water molecules are not included.