9DJZ
CryoEM structures of yeast cytoplasmic dynein in the presence of ATP and Lis1.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dynein heavy chain, cytoplasmic | polymer | 2875 | 331525.0 | 1 | UniProt (P36022) | Saccharomyces cerevisiae (brewer's yeast) | Dynein heavy chain,cytosolic,DYHC |
| 2 | B, C (C, B) | Nuclear distribution protein PAC1 | polymer | 495 | 57030.6 | 2 | UniProt (P39946) | Saccharomyces cerevisiae (brewer's yeast) | Lissencephaly-1 homolog,LIS-1,nudF homolog |
| 3 | D (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | E, F, G (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 5 | H (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 1220 - 4092 (UniProt: P36022)
C, B: 1 - 494 (UniProt: P39946)
| PDB | External Database | Details |
|---|---|---|
| Gly 1220 | Asn 1218 | conflict |
| Phe 1575 | Leu 1575 | conflict |
| Ser 1578 | Phe 1578 | conflict |
| Glu 1668 | Gln 1668 | conflict |
| Val 1777 | Ile 1777 | conflict |
| Val 1984 | Ile 1984 | conflict |
| Val 2936 | Ile 2936 | conflict |
| Gln 3266 | Arg 3266 | conflict |
| Gly 3343 | Ala 3343 | conflict |
| Val 3444 | Ile 3444 | conflict |
| Arg 3556 | Lys 3556 | conflict |
| Asp 3742 | Asn 3742 | conflict |
| Val 3895 | Phe 3895 | conflict |
| Asp 4072 | Asn 4072 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 445586.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1813.1 | |
| All* | Total formula weight | 447399.3 |
