9DIQ

Crystal structure of Apo-H5 hemagglutinin from the influenza virus A/Texas/37/2024 (H5N1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (I, A, C, E, G...)	Hemagglutinin HA1	polymer	325	36534.4	6	UniProt (A0A6B7HPT9) Pfam (PF00509) UniProt (by SIFTS) (A0A869KY97)	Influenza A virus
2	B, D, F, H, J... (J, B, D, F, H...)	Hemagglutinin HA2	polymer	176	20257.3	6	UniProt (A0A6B7HQ27) Pfam (PF00509) UniProt (by SIFTS) (A0A8K1XY81)	Influenza A virus
3	M, O, Q (M, O, Q)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	3	In PDB GlyTouCan (G15407YE)
4	N, P (N, P)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	R (E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6	AA, BA, CA, S, T... (H, K, L, I, A...)	water	water		18.0	41	Chemie (HOH)

Sequence modifications

I, A, C, E, G, K: 11 - 324 (UniProt: A0A6B7HPT9)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag
Met 111	Leu 104	conflict
Gln 122	Leu 115	conflict
Ile 199	Thr 195	conflict
Ala 214	Val 210	conflict

J, B, D, F, H, L: 1 - 174 (UniProt: A0A6B7HQ27)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	340750.3
Branched	Number of molecules	5
	Total formula weight	2608.4
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	343580.0

*Water molecules are not included.