9DIP

Crystal structure of H5 hemagglutinin from the influenza virus A/Texas/37/2024 (H5N1) with LSTa

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, I)	Hemagglutinin HA1	polymer	325	36534.4	3	UniProt (A0A6B7HPT9) Pfam (PF00509) UniProt (by SIFTS) (A0A869KY97)	Influenza A virus
2	B, D, F (B, D, J)	Hemagglutinin HA2	polymer	176	20257.3	3	UniProt (A0A6B7HQ27) Pfam (PF00509) UniProt (by SIFTS) (A0A8K1XY81)	Influenza A virus
3	G (E)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose	branched		836.7	1	In PDB GlyTouCan (G03309JT)
4	H, J (F, H)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose	branched		998.9	2	In PDB GlyTouCan (G08002FG)
5	I (G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	K, L (A, I)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	M, N, O, P, Q... (A, B, C, D, I...)	water	water		18.0	141	Chemie (HOH)

Sequence modifications

A, C, I: 11 - 324 (UniProt: A0A6B7HPT9)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag
Met 111	Leu 104	conflict
Gln 122	Leu 115	conflict
Ile 199	Thr 195	conflict
Ala 214	Val 210	conflict

B, D, J: 1 - 174 (UniProt: A0A6B7HQ27)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	170375.2
Branched	Number of molecules	4
	Total formula weight	3258.9
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	174076.5

*Water molecules are not included.