9DHZ
Cryo-EM structure of HURP bound to a microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Disks large-associated protein 5 | polymer | 291 | 33023.8 | 1 | UniProt (Q15398) | Homo sapiens (human) | DAP-5,Discs large homolog 7,Disks large-associated protein DLG7,Hepatoma up-regulated protein,HURP |
| 2 | B, D (A, K) | Tubulin beta chain | polymer | 445 | 49907.8 | 2 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (pig) | Beta-tubulin |
| 3 | C, E (B, L) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (pig) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
| 4 | F, J (A, K) | TAXOL | non-polymer | 853.9 | 2 | Chemie (TA1) | |||
| 5 | G, K (A, K) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 6 | H, L (B, L) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 7 | I, M (B, L) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
C: 1 - 285 (UniProt: Q15398)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 233248.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3689.2 | |
| All* | Total formula weight | 236937.4 |
