9DHY
Structure of SARS-CoV-2 spike in complex with antibody Fab COVIC-154
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, D, I) | Antibody Fab COVIC-154 Heavy Chain | polymer | 123 | 13371.9 | 3 | Homo sapiens | ||
| 2 | B, E, H (B, E, J) | Antibody Fab COVIC-154 Light Chain | polymer | 107 | 11703.1 | 3 | Homo sapiens | ||
| 3 | C, F, I (C, F, K) | Spike glycoprotein | polymer | 1212 | 134115.7 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 4 | J, K, L, M, N... (M, G, H, N, L...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, BA, CA, DA, EA... (F, K, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) |
Sequence modifications
C, F, K: 14 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met -3 | - | initiating methionine |
| Gly -2 | - | expression tag |
| Val -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Val 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Phe 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ile 6 | - | expression tag |
| Cys 7 | - | expression tag |
| Ile 8 | - | expression tag |
| Ala 9 | - | expression tag |
| Val 10 | - | expression tag |
| Ala 11 | - | expression tag |
| Glu 12 | - | expression tag |
| Ala 13 | - | expression tag |
| Gly 682 | Arg 682 | conflict |
| Ser 683 | Arg 683 | conflict |
| Ser 685 | Arg 685 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 899 | Ala 899 | conflict |
| Pro 942 | Ala 942 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 477572.1 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 3819.6 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4645.4 | |
| All* | Total formula weight | 486037.1 |
