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9DHJ

DHODH in complex with Compound 15

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydroorotate dehydrogenase (quinone), mitochondrialpolymer36939984.71UniProt (Q02127)
Pfam (PF01180)
Homo sapiens (human)DHOdehase,Dihydroorotate oxidase
2B
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3C
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
4D
(A)
(2M,6P)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-7-fluoro-2-(2-methylphenyl)-4-[(2R)-1,1,1-trifluoropropan-2-yl]phthalazin-1(2H)-onenon-polymer491.41Chemie (A1A4M)
5E, F, P, Q, R
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
6AA, BA, G, S, Z
(A)
ACETATE IONnon-polymer59.05Chemie (ACT)
7H
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
8I, J, K, L, M...
(A)
CHLORIDE IONnon-polymer35.57Chemie (CL)
9T
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
10U, V, W, X, Y
(A)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
11CA
(A)
waterwater18.0323Chemie (HOH)
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDBExternal DatabaseDetails
Gly 28-expression tag
Ala 29-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39984.7
Non-Polymers*Number of molecules27
Total formula weight2680.2
All*Total formula weight42664.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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