9DHB

STRUCTURE OF SERINE HYDROXYMETHYLTRANSFERASE 5 FROM GLYCINE MAX CULTIVAR ESSEX COMPLEXED WITH PLP-GLYCINE AND 5-FORMYLTETRAHYDROFOLATE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Serine hydroxymethyltransferase	polymer	496	54644.8	4	UniProt (A0A0R4J3C9) Pfam (PF00464)	Glycine max (soybean)
2	E, I, M, P (A, B, C, D)	N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]	non-polymer		306.2	4	Chemie (PLG)
3	F, J, N, Q (A, B, C, D)	N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid	non-polymer		473.4	4	Chemie (FFO)
4	G, H, K, L, O... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5	S, T, U, V (A, B, C, D)	water	water		18.0	1305	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 471 (UniProt: A0A0R4J3C9)

PDB	External Database	Details
Met -24	-	initiating methionine
Gly -23	-	expression tag
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	218579.2
Non-Polymers*	Number of molecules	14
	Total formula weight	3491.0
All*	Total formula weight	222070.2

*Water molecules are not included.