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9DFX

Cryo-EM structure of a SUR1/Kir6.2 ATP-sensitive potassium channel in the presence of Aekatperone in the closed conformation

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, D, E
(A, B, C, D)
ATP-sensitive inward rectifier potassium channel 11polymer39043661.84UniProt (P70673)
Pfam (PF01007)
Pfam (PF17655)
Rattus norvegicus (Norway rat)BIR,Inward rectifier K(+) channel Kir6.2,Potassium channel,inwardly rectifying subfamily J member 11
2B
(E)
SUR1polymer1582177296.61UniProt (A0A1S4NYG1)
Pfam (PF00664)
Pfam (PF00005)
UniProt (by SIFTS) (A0A1U7R319)
Mesocricetus auratus (golden hamster)
3F, J, M, N, R
(A, E, B, C, D)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.25Chemie (ATP)
4G, H, I, O, P...
(A, C, D)
POTASSIUM IONnon-polymer39.16Chemie (K)
5K
(E)
N-[3-(cyclohexylmethyl)-1H-pyrazol-5-yl]-2-[(1H-imidazol-1-yl)methyl]benzene-1-sulfonamidenon-polymer399.51Chemie (A1A4F)
6L
(E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight351943.6
Non-Polymers*Number of molecules13
Total formula weight3391.2
All*Total formula weight355334.8
*Water molecules are not included.

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PDB entries from 2026-01-28

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