9DFU
X-ray crystal structure of the second Viperin-like enzyme from T. virens variant F40H with bound CTP and SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Radical SAM core domain-containing protein | polymer | 321 | 37369.6 | 1 | UniProt (G9N0G3) Pfam (PF13353) Pfam (PF04055) | Trichoderma virens | |
| 2 | B (A) | CYTIDINE-5'-TRIPHOSPHATE | non-polymer | 483.2 | 1 | Chemie (CTP) | |||
| 3 | C (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 4 | D (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (9865603) PubChem (145712080) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | F (A) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A: 31 - 328 (UniProt: G9N0G3)
| PDB | External Database | Details |
|---|---|---|
| Met 8 | - | initiating methionine |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| Ser 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Val 18 | - | expression tag |
| Asp 19 | - | expression tag |
| Leu 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Thr 22 | - | expression tag |
| Glu 23 | - | expression tag |
| Asn 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Tyr 26 | - | expression tag |
| Phe 27 | - | expression tag |
| Gln 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Met 30 | - | expression tag |
| His 40 | Phe 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37369.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1268.7 | |
| All* | Total formula weight | 38638.2 |
