9DBQ
Cryo-EM structure of human ABCB6 transporter in an inward-facing conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ATP-binding cassette sub-family B member 6 | polymer | 850 | 94971.1 | 2 | UniProt (Q9NP58) Pfam (PF16185) Pfam (PF00664) Pfam (PF00005) | Homo sapiens (human) | ABC-type heme transporter ABCB6,Mitochondrial ABC transporter 3,Mt-ABC transporter 3,P-glycoprotein-related protein,Ubiquitously-expressed mammalian ABC half transporter |
| 2 | C, D, E, F, G... (A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 20 | Chemie (Y01) PubChem (65082) PubChem (363416) PubChem (500055) PubChem (13301926) PubChem (13301927) PubChem (16219150) PubChem (22210610) PubChem (45489984) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A, B: 1 - 842 (UniProt: Q9NP58)
| PDB | External Database | Details |
|---|---|---|
| Asp 843 | - | expression tag |
| Tyr 844 | - | expression tag |
| Lys 845 | - | expression tag |
| Asp 846 | - | expression tag |
| Asp 847 | - | expression tag |
| Asp 848 | - | expression tag |
| Asp 849 | - | expression tag |
| Lys 850 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 189942.3 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 9734.5 | |
| All* | Total formula weight | 199676.8 |
