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9DBO

Crystal structure of a synthetic Fab (R3E9) in complex with the FRB domain of mTOR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Serine/threonine-protein kinase mTORpolymer9311290.91UniProt (P42345)
Pfam (PF08771)
Homo sapiens (human)FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,Mammalian target of rapamycin,mTOR,Mechanistic target of rapamycin,Rapamycin and FKBP12 target 1,Rapamycin target protein 1
2B
(H)
Fab heavy chainpolymer22423866.71Homo sapiens
3C
(L)
Fab light chainpolymer21223109.71Homo sapiens
4D, E, F
(C, H, L)
waterwater18.0548Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight58267.2
All*Total formula weight58267.2
*Water molecules are not included.

248942

PDB entries from 2026-02-11

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