9DBM
Full-length apo human voltage-gated sodium channel 1.8 (NaV1.8), class II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium channel protein type 10 subunit alpha | polymer | 2001 | 225721.3 | 1 | UniProt (Q9Y5Y9) Pfam (PF00520) Pfam (PF06512) Pfam (PF08016) | Homo sapiens (human) | Peripheral nerve sodium channel 3,PN3,hPN3,Sodium channel protein type X subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.8 |
| 2 | B, C, D, E, F (B, C, D, E, F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 3 | G, H, I, J, V (A) | CHOLESTEROL | non-polymer | 386.7 | 5 | Chemie (CLR) | |||
| 4 | K, N, O (A) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 3 | Chemie (PCW) | |||
| 5 | L, M, P, Q, R... (A) | 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 510.7 | 6 | Chemie (LPE) | |||
| 6 | T, U (A) | O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | non-polymer | 792.1 | 2 | Chemie (P5S) |
Sequence modifications
A: 1 - 1956 (UniProt: Q9Y5Y9)
| PDB | External Database | Details |
|---|---|---|
| Asp -44 | - | expression tag |
| Tyr -43 | - | expression tag |
| Lys -42 | - | expression tag |
| Asp -41 | - | expression tag |
| Asp -40 | - | expression tag |
| Asp -39 | - | expression tag |
| Asp -38 | - | expression tag |
| Lys -37 | - | expression tag |
| Ser -36 | - | expression tag |
| Ala -35 | - | expression tag |
| Trp -34 | - | expression tag |
| Ser -33 | - | expression tag |
| His -32 | - | expression tag |
| Pro -31 | - | expression tag |
| Gln -30 | - | expression tag |
| Phe -29 | - | expression tag |
| Glu -28 | - | expression tag |
| Lys -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Ser -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ala -15 | - | expression tag |
| Trp -14 | - | expression tag |
| Ser -13 | - | expression tag |
| His -12 | - | expression tag |
| Pro -11 | - | expression tag |
| Gln -10 | - | expression tag |
| Phe -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Val 1713 | Met 1713 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 225721.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2932.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 8943.0 | |
| All* | Total formula weight | 237597.0 |
