9DB6
Sialidase682 co-crystallized with inhibitor DANA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | BNR/Asp-box repeat protein | polymer | 540 | 60547.9 | 4 | UniProt (C9KXU6) Pfam (PF14873) Pfam (PF13859) UniProt (by SIFTS) (K5BUM2) | Bacteroides finegoldii DSM 17565 | |
| 2 | E, F, G, H (A, B, C, D) | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID | non-polymer | 291.3 | 4 | Chemie (DAN) PubChem (65309) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1040 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 530 (UniProt: C9KXU6)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 4 | Thr 24 | conflict |
| Thr 18 | Ile 38 | conflict |
| Lys 37 | Glu 57 | conflict |
| Asp 38 | Glu 58 | conflict |
| Leu 41 | Phe 61 | conflict |
| Leu 55 | Gln 75 | conflict |
| Asp 75 | Asn 95 | conflict |
| Arg 78 | Cys 98 | conflict |
| Gly 87 | Ser 107 | conflict |
| Lys 157 | Arg 177 | conflict |
| Val 158 | Asp 178 | conflict |
| Asp 160 | Thr 180 | conflict |
| Glu 231 | Lys 251 | conflict |
| Arg 368 | Gln 388 | conflict |
| Gln 444 | Leu 464 | conflict |
| Pro 491 | Ser 511 | conflict |
| Leu 527 | Ile 547 | conflict |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
| His 538 | - | expression tag |
| His 539 | - | expression tag |
| His 540 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 242191.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1165.0 | |
| All* | Total formula weight | 243356.6 |
