9DAQ
Structure of E. coli dihydrofolate reductase (DHFR) in an occluded conformation and in complex with a cycloguanil derivative
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 161 | 18244.6 | 1 | UniProt (P0ABQ5) Pfam (PF00186) UniProt (by SIFTS) (P0ABQ4) | Escherichia coli | |
| 2 | B (A) | (6S)-1-(4-chlorophenyl)-6-ethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine | non-polymer | 251.7 | 1 | Chemie (A1A3E) | |||
| 3 | C (A) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ5)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18244.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 251.7 | |
| All* | Total formula weight | 18496.3 |
