9DA6
Crystal structure of human DNPH1 bound to inhibitor 3a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 5-hydroxymethyl-dUMP N-hydrolase | polymer | 145 | 16224.2 | 2 | UniProt (O43598) Pfam (PF05014) | Homo sapiens (human) | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1,c-Myc-responsive protein RCL |
| 2 | C, E (A, B) | PHOSPHORIC ACID MONO-(4-HYDROXY-PYRROLIDIN-3-YLMETHYL) ESTER | non-polymer | 197.1 | 2 | Chemie (NRI) PubChem (49867400) | |||
| 3 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 162 (UniProt: O43598)
| PDB | External Database | Details |
|---|---|---|
| Ser 18 | - | expression tag |
| Met 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32448.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 456.3 | |
| All* | Total formula weight | 32904.8 |
