9DA4
Crystal structure of human DNPH1 bound to inhibitor 2b
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5-hydroxymethyl-dUMP N-hydrolase | polymer | 145 | 16224.2 | 1 | UniProt (O43598) Pfam (PF05014) | Homo sapiens (human) | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1,c-Myc-responsive protein RCL |
| 2 | B (A) | {(3R,4R)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-hydroxypyrrolidin-3-yl}methyl dihydrogen phosphate | non-polymer | 343.3 | 1 | Chemie (A1BBE) | |||
| 3 | C (A) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A: 20 - 162 (UniProt: O43598)
| PDB | External Database | Details |
|---|---|---|
| Ser 18 | - | expression tag |
| Met 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16224.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 343.3 | |
| All* | Total formula weight | 16567.5 |
