9DA3
Crystal structure of human DNPH1 bound to inhibitor 2a
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 5-hydroxymethyl-dUMP N-hydrolase | polymer | 145 | 16224.2 | 2 | UniProt (O43598) Pfam (PF05014) | Homo sapiens (human) | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1,c-Myc-responsive protein RCL |
| 2 | C, D (A, B) | [(3R,4R)-4-hydroxy-1-{[5-(hydroxymethyl)-6-oxo-1,6-dihydropyridin-3-yl]methyl}pyrrolidin-3-yl]methyl dihydrogen phosphate | non-polymer | 334.3 | 2 | Chemie (A1BBD) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 162 (UniProt: O43598)
| PDB | External Database | Details |
|---|---|---|
| Ser 18 | - | expression tag |
| Met 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32448.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 668.5 | |
| All* | Total formula weight | 33117.0 |
