9D9T
Human norovirus GII.4 Sydney protease R112A mutant in complex with rupintrivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidase C37 | polymer | 183 | 19398.4 | 1 | UniProt (K4L8Z7) Pfam (PF05416) | Norovirus | |
| 2 | B (A) | 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | non-polymer | 600.7 | 1 | Chemie (AG7) | |||
| 3 | C, D, E, F, G (A) | IODIDE ION | non-polymer | 126.9 | 5 | Chemie (IOD) | |||
| 4 | H (A) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: K4L8Z7)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ala 112 | Arg 1120 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19398.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1235.2 | |
| All* | Total formula weight | 20633.5 |
