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9D9Q

Crystal structure of IgG1 FC M252R at pH 8.0

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Immunoglobulin gamma-1 heavy chain Fc fragmentpolymer23125990.52UniProt (P0DOX5)Homo sapiens (human)Immunoglobulin gamma-1 heavy chain NIE
Sequence modifications
B, A: 236 - 447 (UniProt: P0DOX5)
PDBExternal DatabaseDetails
Met 217-initiating methionine
Gly 218-expression tag
Trp 219-expression tag
Ser 220-expression tag
Cys 221-expression tag
Ile 222-expression tag
Ile 223-expression tag
Leu 224-expression tag
Phe 225-expression tag
Leu 226-expression tag
Val 227-expression tag
Ala 228-expression tag
Thr 229-expression tag
Ala 230-expression tag
Thr 231-expression tag
Gly 232-expression tag
Val 233-expression tag
His 234-expression tag
Ser 235-expression tag
Arg 252Met 254engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51980.9
All*Total formula weight51980.9
*Water molecules are not included.

255239

PDB entries from 2026-06-17

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