9D74
CryoEM structure of anti-MHC-I Fab B1.23.2 complex with HLA-B44:05
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen B alpha chain (HLA-B*44:05) | polymer | 274 | 31802.1 | 1 | UniProt (Q860B7) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) | Homo sapiens (human) | |
| 3 | C (H) | B1.23.2 Fab Heavy Chain: CH and CH1 domains | polymer | 214 | 22845.6 | 1 | Homo sapiens | ||
| 4 | D (L) | B1.23.2 Fab Light Chain: VL and C kappa domains | polymer | 213 | 23846.4 | 1 | Homo sapiens | ||
| 5 | E (P) | MHC class II antigen peptide | polymer | 9 | 1090.2 | 1 | UniProt (Q9TQB0) | synthetic construct |
Sequence modifications
A: 2 - 274 (UniProt: Q860B7)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 91463.6 | |
| All* | Total formula weight | 91463.6 |
