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9D61

Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic , no scFv16

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kappa-type opioid receptorpolymer38042681.01UniProt (P41145)
Pfam (PF00001)
Homo sapiens (human)K-OR-1,KOR-1
2B
(C)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34037416.91UniProt (P62873)
Pfam (PF00400)
Homo sapiens (human)Transducin beta chain 1
3C
(D)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
4D
(B)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440415.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
5E
(A)
(3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamidenon-polymer465.61Chemie (JDC)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight128374.1
Non-Polymers*Number of molecules1
Total formula weight465.6
All*Total formula weight128839.8
*Water molecules are not included.

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PDB entries from 2026-01-14

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