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9D52

Structure of PAK4 in complex with compound 18

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase PAK 4polymer29333098.41UniProt (O96013)
Pfam (PF00069)
Homo sapiens (human)p21-activated kinase 4,PAK-4
2B
(A)
2-cyano-N-[3-({6-[(5-cyclopropyl-1,3-thiazol-2-yl)amino]pyrazin-2-yl}amino)bicyclo[1.1.1]pentan-1-yl]acetamidenon-polymer381.51Chemie (A1A2R)
3C, D, E
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4F
(A)
waterwater18.042Chemie (HOH)
Sequence modifications
A: 300 - 591 (UniProt: O96013)
PDBExternal DatabaseDetails
Ser 299-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33098.4
Non-Polymers*Number of molecules4
Total formula weight567.7
All*Total formula weight33666.1
*Water molecules are not included.

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PDB entries from 2025-12-03

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