9D4A
Atomic model of Ketoacyl Reductase domain and 4 helical bundle of S. cerevisiae Fatty Acid Synthase (FAS) in complex with octanoyl-CoA (in vitro binding)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, E, I, M, Q...) | Fatty acid synthase subunit beta | polymer | 2051 | 228838.3 | 6 | UniProt (P07149) Pfam (PF17828) Pfam (PF16073) Pfam (PF08354) Pfam (PF17951) Pfam (PF13452) Pfam (PF22235) Pfam (PF01575) Pfam (PF00698) | Saccharomyces cerevisiae (brewer's yeast) | |
| 2 | B, D, F, H, J... (B, F, J, N, R...) | Fatty acid synthase subunit alpha | polymer | 1887 | 207152.4 | 6 | UniProt (P19097) Pfam (PF18314) Pfam (PF00109) Pfam (PF02801) Pfam (PF01648) Pfam (PF18325) | Saccharomyces cerevisiae (brewer's yeast) | |
| 3 | M, O, Q, S, U... (A, E, I, M, Q...) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 6 | Chemie (FMN) | |||
| 4 | N, P, R, T, V... (B, F, J, N, R...) | S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate | non-polymer | 484.5 | 6 | Chemie (SXO) | |||
| 5 | AA, BA, CA, DA, EA... (E, F, I, J, M...) | water | water | 18.0 | 3060 | Chemie (HOH) |
Sequence modifications
A, E, I, M, Q, U: 1 - 2051 (UniProt: P07149)
B, F, J, N, R, V: 1 - 1887 (UniProt: P19097)
| PDB | External Database | Details |
|---|---|---|
| Ala 274 | Ser 274 | variant |
| Ala 1834 | Arg 1834 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ala 1305 | Cys 1305 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 2615943.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5645.3 | |
| All* | Total formula weight | 2621589.0 |
