9D32

Structure of the HKU5 RBD bound to the P. abramus ACE2 receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Angiotensin-converting enzyme	polymer	768	89172.9	1	UniProt (C7ECT9) Pfam (PF01401) Pfam (PF16959)	Pipistrellus abramus	ACE2
2	B (B)	Spike glycoprotein	polymer	267	29224.8	1	UniProt (S4WZQ4) Pfam (PF09408) UniProt (by SIFTS) (A3EXD0)	Pipistrellus bat coronavirus HKU5	S glycoprotein,E2,Peplomer protein
3	C (C)	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
4	D, E, F, G, H... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
5	J (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 17 - 724 (UniProt: C7ECT9)

PDB	External Database	Details
Met -6	-	expression tag
Pro -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Leu -1	-	expression tag
Gln 0	-	expression tag
Pro 1	-	expression tag
Leu 2	-	expression tag
Ala 3	-	expression tag
Thr 4	-	expression tag
Leu 5	-	expression tag
Tyr 6	-	expression tag
Leu 7	-	expression tag
Leu 8	-	expression tag
Gly 9	-	expression tag
Met 10	-	expression tag
Leu 11	-	expression tag
Val 12	-	expression tag
Ala 13	-	expression tag
Ser 14	-	expression tag
Val 15	-	expression tag
Leu 16	-	expression tag
Leu 725	-	expression tag
Val 726	-	expression tag
Pro 727	-	expression tag
Arg 728	-	expression tag
Gly 729	-	expression tag
Ser 730	-	expression tag
Ser 731	-	expression tag
Ser 732	-	expression tag
Gly 733	-	expression tag
Gly 734	-	expression tag
Ser 735	-	expression tag
Gly 736	-	expression tag
Leu 737	-	expression tag
Asn 738	-	expression tag
Asp 739	-	expression tag
Ile 740	-	expression tag
Phe 741	-	expression tag
Glu 742	-	expression tag
Ala 743	-	expression tag
Gln 744	-	expression tag
Lys 745	-	expression tag
Ile 746	-	expression tag
Glu 747	-	expression tag
Trp 748	-	expression tag
His 749	-	expression tag
Glu 750	-	expression tag
Gly 751	-	expression tag
Gly 752	-	expression tag
Ser 753	-	expression tag
His 754	-	expression tag
His 755	-	expression tag
His 756	-	expression tag
His 757	-	expression tag
His 758	-	expression tag
His 759	-	expression tag
His 760	-	expression tag
His 761	-	expression tag

B: 389 - 587 (UniProt: S4WZQ4)

PDB	External Database	Details
Met 358	-	expression tag
Gly 359	-	expression tag
Ile 360	-	expression tag
Leu 361	-	expression tag
Pro 362	-	expression tag
Ser 363	-	expression tag
Pro 364	-	expression tag
Gly 365	-	expression tag
Met 366	-	expression tag
Pro 367	-	expression tag
Ala 368	-	expression tag
Leu 369	-	expression tag
Leu 370	-	expression tag
Ser 371	-	expression tag
Leu 372	-	expression tag
Val 373	-	expression tag
Ser 374	-	expression tag
Leu 375	-	expression tag
Leu 376	-	expression tag
Ser 377	-	expression tag
Val 378	-	expression tag
Leu 379	-	expression tag
Leu 380	-	expression tag
Met 381	-	expression tag
Gly 382	-	expression tag
Cys 383	-	expression tag
Val 384	-	expression tag
Ala 385	-	expression tag
Glu 386	-	expression tag
Thr 387	-	expression tag
Gly 388	-	expression tag
Leu 588	-	expression tag
Val 589	-	expression tag
Pro 590	-	expression tag
Arg 591	-	expression tag
Gly 592	-	expression tag
Ser 593	-	expression tag
Ser 594	-	expression tag
Ser 595	-	expression tag
Gly 596	-	expression tag
Gly 597	-	expression tag
Ser 598	-	expression tag
Gly 599	-	expression tag
Leu 600	-	expression tag
Asn 601	-	expression tag
Asp 602	-	expression tag
Ile 603	-	expression tag
Phe 604	-	expression tag
Glu 605	-	expression tag
Ala 606	-	expression tag
Gln 607	-	expression tag
Lys 608	-	expression tag
Ile 609	-	expression tag
Glu 610	-	expression tag
Trp 611	-	expression tag
His 612	-	expression tag
Glu 613	-	expression tag
Gly 614	-	expression tag
Gly 615	-	expression tag
Ser 616	-	expression tag
His 617	-	expression tag
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag
His 624	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	118397.7
Branched	Number of molecules	1
	Total formula weight	367.3
Non-Polymers*	Number of molecules	9
	Total formula weight	1835.1
All*	Total formula weight	120600.2

*Water molecules are not included.