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9D12

Smarca2 Bromodomain in complex with compound 15

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Isoform Short of Probable global transcription activator SNF2L2polymer12414434.53UniProt (P51531)
Pfam (PF00439)
Homo sapiens (human)ATP-dependent helicase SMARCA2,BRG1-associated factor 190B,BAF190B,Protein brahma homolog,hBRM,SNF2-alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
2D, H, K
(A, B, C)
ZINC IONnon-polymer65.43Chemie (ZN)
3E, I, L
(A, B, C)
(12'R)-4'-chloro-9'-(piperidin-4-yl)-5'H-spiro[cyclohexane-1,7'-indolo[1,2-a]quinazolin]-5'-onenon-polymer419.93Chemie (A1A1P)
4F, G, J
(A, B)
ACETATE IONnon-polymer59.03Chemie (ACT)
5M, N, O
(A, B, C)
waterwater18.0142Chemie (HOH)
Sequence modifications
A, B, C: 1373 - 1493 (UniProt: P51531)
PDBExternal DatabaseDetails
Ser 1370-expression tag
Asn 1371-expression tag
Ala 1372-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight43303.6
Non-Polymers*Number of molecules9
Total formula weight1633.2
All*Total formula weight44936.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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