9D0V
Crystal structure of CDK2/CyclinE1 in complex with Cpd 2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 2 | polymer | 298 | 34056.5 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | B (B) | G1/S-specific cyclin-E1 | polymer | 286 | 33220.6 | 1 | UniProt (P24864) Pfam (PF00134) Pfam (PF02984) | Homo sapiens (human) | |
| 3 | C (A) | 6-chloro-8-cyclopentyl-2-[4-(ethanesulfonyl)-2-methylanilino]pyrido[2,3-d]pyrimidin-7(8H)-one | non-polymer | 446.9 | 1 | Chemie (A1A1H) | |||
| 4 | D (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | E, F, G (B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | H, I, J (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | K, L (A, B) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
B: 81 - 363 (UniProt: P24864)
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | - | expression tag |
| Gly 79 | - | expression tag |
| Ser 80 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67277.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1015.6 | |
| All* | Total formula weight | 68292.6 |
