9D0S
Crystal structure of human Wee1 kinase domain in complex with inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Wee1-like protein kinase | polymer | 289 | 32485.0 | 1 | UniProt (P30291) Pfam (PF00069) | Homo sapiens (human) | WEE1hu,Wee1A kinase |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | C, D, E, F, G... (A) | CHLORIDE ION | non-polymer | 35.5 | 13 | Chemie (CL) | |||
| 4 | P (A) | (8P)-3-(2,6-dichlorophenyl)-1-methyl-8-[1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl]-1,2,3,7-tetrahydro-4H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-4-one | non-polymer | 510.4 | 1 | Chemie (A1A1R) | |||
| 5 | Q (A) | water | water | 18.0 | 448 | Chemie (HOH) |
Sequence modifications
A: 291 - 575 (UniProt: P30291)
| PDB | External Database | Details |
|---|---|---|
| Gly 287 | - | expression tag |
| Ala 288 | - | expression tag |
| Met 289 | - | expression tag |
| Gly 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32485.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 994.3 | |
| All* | Total formula weight | 33479.3 |
