9D0Q
Crystal structure of human Wee1 kinase domain in complex with inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Wee1-like protein kinase | polymer | 289 | 32485.0 | 2 | UniProt (P30291) Pfam (PF00069) | Homo sapiens (human) | WEE1hu,Wee1A kinase |
| 2 | C, M (A, B) | 1-[(6R)-6-(2,6-dichlorophenyl)-8-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]-7,8-dihydropteridin-5(6H)-yl]ethan-1-one | non-polymer | 526.5 | 2 | Chemie (A1A1S) | |||
| 3 | D, N (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, F, G, H, I... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 17 | Chemie (CL) | |||
| 5 | X, Y (A, B) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A, B: 291 - 575 (UniProt: P30291)
| PDB | External Database | Details |
|---|---|---|
| Gly 287 | - | expression tag |
| Ala 288 | - | expression tag |
| Met 289 | - | expression tag |
| Gly 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64970.0 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1701.6 | |
| All* | Total formula weight | 66671.6 |
