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9CYQ

Crystal structure of Q78R mutant human PTP1B (PTPN1) at room temperature (298 K)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer32137470.81UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B,PTP-1B
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C
(A)
waterwater18.061Chemie (HOH)
Sequence modifications
A: 1 - 321 (UniProt: P18031)
PDBExternal DatabaseDetails
Arg 78Gln 78engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37470.8
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight37495.1
*Water molecules are not included.

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PDB entries from 2025-07-23

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