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9CYP

Crystal structure of I19V mutant human PTP1B (PTPN1) at room temperature (298 K)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer32137427.71UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B,PTP-1B
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C
(A)
waterwater18.094Chemie (HOH)
Sequence modifications
A: 1 - 321 (UniProt: P18031)
PDBExternal DatabaseDetails
Val 19Ile 19engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37427.7
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight37452.0
*Water molecules are not included.

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PDB entries from 2025-07-23

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