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9CYD

SARS-CoV-2 PLpro in complex with inhibitor WEHI-P4

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Papain-like proteasepolymer31835927.71UniProt (P0DTC1)
Pfam (PF08715)
Severe acute respiratory syndrome coronavirus 2Non-structural protein 3, nsp3, PL2-PRO, Papain-like proteinase, PL-PRO
2B
(A)
(1S,4s)-4-{(3R)-3-[(E)-(methoxyimino)(6-methoxynaphthalen-2-yl)methyl]piperidin-1-yl}cyclohexan-1-olnon-polymer396.51Chemie (A1A0U)
PubChem (177314105)
PubChem (172914174)
3C, D
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
4E
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
PubChem (312)
Sequence modifications
A: 1 - 315 (UniProt: P0DTC1)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Ser 111Cys 1674engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35927.7
Non-Polymers*Number of molecules4
Total formula weight562.8
All*Total formula weight36490.5
*Water molecules are not included.

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PDB entries from 2026-04-15

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