9CY8
Constrained b-hairpins targeting the EphA4 ligand binding domain
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin type-A receptor 4 | polymer | 185 | 21259.1 | 1 | UniProt (P54764) Pfam (PF01404) | Homo sapiens (human) | EPH-like kinase 8,EK8,hEK8,Tyrosine-protein kinase TYRO1,Tyrosine-protein kinase receptor SEK |
| 2 | B (B) | Constrained b-hairpin | polymer | 13 | 1518.7 | 1 | synthetic construct | ||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A: 29 - 209 (UniProt: P54764)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| His 27 | - | expression tag |
| Met 28 | - | expression tag |
| Ala 204 | Cys 204 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22777.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 22813.3 |
