9CXL
Crystal structure of IgG1 FC WT at pH 5.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Immunoglobulin gamma-1 heavy chain Fc Fragment | polymer | 231 | 25964.5 | 2 | UniProt (P0DOX5) | Homo sapiens (human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | C (C) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1219.1 | 1 | In PDB GlyTouCan (G32156ZV) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A, B: 236 - 447 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Met 217 | - | initiating methionine |
| Gly 218 | - | expression tag |
| Trp 219 | - | expression tag |
| Ser 220 | - | expression tag |
| Cys 221 | - | expression tag |
| Ile 222 | - | expression tag |
| Ile 223 | - | expression tag |
| Leu 224 | - | expression tag |
| Phe 225 | - | expression tag |
| Leu 226 | - | expression tag |
| Val 227 | - | expression tag |
| Ala 228 | - | expression tag |
| Thr 229 | - | expression tag |
| Ala 230 | - | expression tag |
| Thr 231 | - | expression tag |
| Gly 232 | - | expression tag |
| Val 233 | - | expression tag |
| His 234 | - | expression tag |
| Ser 235 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51928.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1219.1 | |
| All* | Total formula weight | 53148.0 |
