9CXI

Structure of PDE6C in complex with the rod inhibitory p gamma subunit in the absence of added cGMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	polymer	843	97724.6	2	UniProt (P51160) Pfam (PF01590) Pfam (PF00233)	Homo sapiens (human)	cGMP phosphodiesterase 6C
2	C, D (C, D)	rod pg	polymer	99	11055.7	2	Pfam (PF04868) UniProt (by SIFTS) (P04972)	Mus musculus (mouse)
3	E, H (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	F, I (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
5	G, J (A, B)	CYCLIC GUANOSINE MONOPHOSPHATE	non-polymer		345.2	2	Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904)

Sequence modifications

A, B: 2 - 830 (UniProt: P51160)

PDB	External Database	Details
Gly -12	-	expression tag
Pro -11	-	expression tag
Thr -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	217560.7
Non-Polymers*	Number of molecules	6
	Total formula weight	869.8
All*	Total formula weight	218430.5

*Water molecules are not included.