9CX1
Crystal structure of HLA-A*03:01 L156Q mutant in complex with a mutant PIK3CA peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A alpha chain | polymer | 274 | 31643.8 | 1 | UniProt (P04439) | Homo sapiens (human) | Human leukocyte antigen A,HLA-A |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) | Homo sapiens (human) | |
| 3 | C (C) | Mutant PIK3CA peptide | polymer | 9 | 972.1 | 1 | UniProt (P42336) | Homo sapiens | |
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F, G (A, B, C) | water | water | 18.0 | 379 | Chemie (HOH) |
Sequence modifications
A: 1 - 274 (UniProt: P04439)
B: 1 - 99 (UniProt: P61769)
C: 1 - 9 (UniProt: P42336)
| PDB | External Database | Details |
|---|---|---|
| Gln 156 | Leu 180 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Leu 2 | His 1047 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44495.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 44587.4 |
